San Diego, CA Commercial Real Estate - Office, Warehouses, and Retail Space

Office spaces in San Diego are seeing increasing demand from technology and life sciences firms, particularly in hubs like UTC, Sorrento Valley, and Downtown. The industrial market remains strong due to e-commerce growth and the region's strategic logistics advantages. Retail spaces are rebounding, with a focus on experiential and mixed-use developments catering to the city's vibrant population and tourism industry. San Diego's business-friendly climate, highly educated workforce, and strong research institutions, including UC San Diego, attract companies seeking innovation and collaboration. Additionally, the city's quality of life—boasting year-round mild weather, cultural amenities, and outdoor activities—further draws talent and businesses to the area.

Rofo researches and displays commercial real estate listings from top brokerage firms and landlords in San Diego, CA making it easier to find available commercial space and compare current asking rental rates. In San Diego, CA there are currently 1,454 office spaces for lease, 289 warehouse spaces for rent, 223 retail spaces, and 230 shared office spaces (also known as co-working spaces and executive suites) with 167 real estate professionals to help you find the right space for you. Sizes range from 200 square feet up to 10,997,805 square feet. Filter your search below and get free advice from recommended brokers in San Diego, CA.

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Showing 1 - 20 of 872 buildings with 2,041 total listings

3111 Camino del Rio N, San Diego, CA 92108

3111 Camino del Rio N is an office property for lease in San Diego, CA. The property currently has 11 office spaces for lease and is marketed by Regus.

Centerside consists of two striking towers in the heart of Mission Valley. The 13 and 16-story towers include 490,000 SF of office space with...

11 office spaces from 11 to 1,992 square feet.

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2305 Historic Decatur Rd, San Diego, CA 92106

2305 Historic Decatur Rd is an office property for lease in San Diego, CA. The property currently has 12 office spaces for lease and is marketed by CBRE San Diego and Regus.

105,061 SF Class A Office Building

12 office spaces from 11 to 6,605 square feet.

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10620 Treena St, San Diego, CA 92131

10620 Treena St is an office property for lease in San Diego, CA. The property currently has 11 office spaces for lease and is marketed by Regus.

Centrally located in Scripps Ranch, fronting Interstate 8. Equal distance from State Route 52 and 56. Adjacent communities of Mira Mesa, Carmel...

11 office spaces from 11 to 1,076 square feet.

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501 W Broadway, San Diego, CA 92101

501 W Broadway is an office property for lease in San Diego, CA. The property currently has 13 office spaces for lease and is marketed by , ABCNRegus and Search Office Space.

With its distinctive arched entry, granite exterior and marble finishes, this is one of Downtown’s finest jewels. Panoramic views and an...

13 office spaces from 11 to 13,478 square feet.

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12707 & 12777 High Bluff Drive, San Diego, CA 92130

12707 & 12777 High Bluff Drive is an office property for lease in San Diego, CA. The property currently has 15 office spaces for lease and is marketed by Cassidy Turley BRE and Regus.

Major Renovations coming soon including new hardscape, enhanced exterior facades, new lobby, corridors and restrooms, new signage, enhanced courtyard...

15 office spaces from 3,223 to 7,062 square feet.

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9920 Pacific Heights Blvd, San Diego, CA 92121

9920 Pacific Heights Blvd is an office property for lease in San Diego, CA. The property currently has 14 office spaces for lease and is marketed by Cassidy Turley BRE and Regus.

Nestled in the thriving Sorrento Valley district of San Diego, 99Twenty at 9920 Pacific Heights Blvd is a modern commercial office building designed...

14 office spaces from 11 to 14,076 square feet.

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350 10th Avenue, San Diego, CA 92101

350 10th Avenue is an office property for lease in San Diego, CA. The property currently has 11 office spaces for lease and is marketed by Regus.

this 306,750 SF Class A office tower provides 15 floors with amazing views to all levels of the stadium, downtown and the bay.

11 office spaces from 11 to 1,076 square feet.

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845 15th St, San Diego, CA 92101

845 15th St is an office property for lease in San Diego, CA. The property currently has 9 office spaces for lease and is marketed by Regus.

ITS TIME TO CREATE AT SPACES MAKERS QUARTER IN SAN DIEGO. East Village, San Diego, has become a nexus of redevelopment in SoCal, with the new-build...

9 office spaces from 11 to 1,076 square feet.

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1420 Kettner Blvd, San Diego, CA 92101

1420 Kettner Blvd is an office property for lease in San Diego, CA. The property currently has 10 office spaces for lease and is marketed by Regus.

Engage with a community of like-minded professionals at Kettner Commons Located on the south side of the chic and attractive Little Italy neighborhood,...

10 office spaces from 11 to 1,076 square feet.

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4445 Eastgate Mall, Suite 200, San Diego, CA 92121

4445 Eastgate Mall, Suite 200 is an office property for lease in San Diego, CA. The property currently has 11 office spaces for lease and is marketed by Regus.

Dynamic campus community You!lmost guaranteed to learn something while working from University City. Minutes from the San Diego campus, Sunroad...

11 office spaces from 11 to 1,076 square feet.

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770 First Avenue, San Diego, CA 92101

770 First Avenue is an office property for lease in San Diego, CA. The property currently has 12 office spaces for lease and is marketed by Regus.

Virtual office in CA, San Diego - 770 First Avenue

12 office spaces from 54 to 1,292 square feet.

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550 Front St, San Diego, CA 92101

550 Front St is a retail property for lease in San Diego, CA. The property currently has 2 retail spaces for lease and is marketed by Cassidy Turley BRE.

2 retail spaces from 1,995 to 3,459 square feet.

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8690 Aero Dr, San Diego, CA 92123

8690 Aero Dr is a retail property for lease in San Diego, CA. The property currently has 1 retail space for lease and is marketed by Cassidy Turley BRE.

Located at Signalized Intersection at the Main Entrance to Montgomery Field Airport Northwest Corner Aero Drive & John J. Montgomery Drive Surrounded...

1 retail space from 960 to 2,730 square feet.

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9520 Padgett St, San Diego, CA 92126

9520 Padgett St is a mixed-use property for lease in San Diego, CA. The property currently has 2 office spaces and 5 retail spaces for lease and is marketed by Cassidy Turley BRE and Voit Commercial.

High image multi-tenant business park Recently renovated interior and exterior Centally located and minutes from freeways

2 office spaces and 5 retail spaces from 743 to 5,744 square feet.

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1970 Columbia St, San Diego, CA 92101

1970 Columbia St is a retail property for lease in San Diego, CA. The property currently has 1 retail space for lease and is marketed by Cassidy Turley BRE.

Address is 1970-2020 Columbia - Vanilla Shell Condition
Onsite parking negotiable - Situated below a 184 unit residential project

1 retail space 1,065 square feet.

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3955 5th Ave, San Diego, CA 92103

3955 5th Ave is a retail property for lease in San Diego, CA. The property currently has 3 retail spaces for lease and is marketed by Cassidy Turley BRE.

3 retail spaces from 398 to 3,712 square feet.

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4427 Rainier Ave, San Diego, CA 92120

4427 Rainier Ave is a mixed-use property for lease in San Diego, CA. The property currently has , 2 industrial spaces2 office spaces and 1 retail space for lease and is marketed by and Cassidy Turley BRE.

Ideal location with easy access to I-15 and I-8.

, 2 industrial spaces 2 office spaces and 1 retail space from 1,375 to 15,675 square feet.

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1025 W Laurel St, San Diego, CA 92101

1025 W Laurel St is a retail property for lease in San Diego, CA. The property currently has 3 retail spaces for lease and is marketed by Lee and Associates San Diego.

San Diego

3 retail spaces from 1,113 to 3,954 square feet.

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8199 Clairemont Mesa Blvd, San Diego, CA 92111

8199 Clairemont Mesa Blvd is a retail property for lease in San Diego, CA. The property currently has 1 retail space for lease and is marketed by Voit Commercial.

Kearny Plaza features National and regional co-tenants, excellent visibility, great signage, ample parking, and is located on two signalized...

1 retail space from 1,200 to 3,148 square feet.

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707 Broadway, San Diego, CA 92101

707 Broadway is a retail property for lease in San Diego, CA. The property currently has 1 retail space for lease and is marketed by CBRE San Diego.

707 Broadway is a 19-story building in downtown, which is only 5 blocks from Petco Park and walking distance to the Gaslamp District. The building...

1 retail space 10,997,805 square feet.

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