San Diego, CA Commercial Real Estate - Office, Warehouses, and Retail Space

San Diego's commercial real estate market is experiencing a notable shift in office leasing dynamics, with current vacancy rates hovering around 13 percent, driven primarily by a hybrid work model. While larger companies are downsizing their footprints, the demand for flexible workspace solutions is on the rise, particularly in the coworking segment, which continues to thrive as small businesses seek adaptable options. Coworking spaces now make up a significant share of the market, catering to startups and freelancers who prioritize flexibility and community. Health indicators, such as rising rental rates in prime areas, signal a competitive landscape for quality spaces, but small businesses should strategize on leases that offer short term commitments and growth potential. Key insights for these businesses include focusing on neighborhoods with strong amenities and transportation access, as these aspects enhance employee satisfaction and retention. Overall, navigating the current market requires a keen understanding of emerging trends and tailored approaches to leasing.

Rofo researches and displays commercial real estate listings from top brokerage firms and landlords in San Diego, CA making it easier to find available commercial space and compare current asking rental rates. In San Diego, CA there are currently 1,454 office spaces for lease, 289 warehouse spaces for rent, 223 retail spaces, and 230 shared office spaces (also known as co-working spaces and executive suites) with 167 real estate professionals to help you find the right space for you. Sizes range from 200 square feet up to 10,997,805 square feet. Filter your search below and get free advice from recommended brokers in San Diego, CA.

sort by: Rofo sort | size | price

Showing 1 - 20 of 197 buildings with 219 total listings

3160 Camino del Rio S, San Diego, CA 92108

3160 Camino del Rio S is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by CBC Corporate.

Located in the heart of Mission Valley with nearby access to I-8, I-15 and I-805

1 office space

Add to list
5755 Oberlin Dr, San Diego, CA 92121

5755 Oberlin Dr is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by Cassidy Turley BRE.

1 office space from 1,292 to 2,883 square feet.

Add to list
2188 San Diego Ave, San Diego, CA 92110

2188 San Diego Ave is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by Cassidy Turley BRE.

1 office space 7,433 square feet.

Add to list
9932 Mesa Rim Rd, San Diego, CA 92121

9932 Mesa Rim Rd is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by Commercial Properties Services.

1 office space 15,308 square feet.

Add to list
3572 University Ave, San Diego, CA 92104

3572 University Ave is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by CBC Corporate.

1 office space

Add to list
6175 Progressive Dr, San Diego, CA 92154

6175 Progressive Dr is an office property for lease in San Diego, CA. The property currently has 2 office spaces for lease and is marketed by CBC Corporate.

2 office spaces

Add to list
1440 Morena Blvd, San Diego, CA 92110

1440 Morena Blvd is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by CBC Corporate.

• Excellent development opportunity • Current structures include a single family residence, two duplexes, and garage • Great location on...

1 office space

Add to list
133 W San Ysidro Blvd, San Diego, CA 92173

133 W San Ysidro Blvd is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by CBC Corporate.

Rosa A. Cabrera 619-962-2535 rcsellshomes@gmail.com

1 office space

Add to list
4364 50th St, San Diego, CA 92115

4364 50th St is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by CBC Corporate.

Highly sought after area, located very close to San Diego State University (SDSU) 1/2 block from Talmadge. This 9-Unit property has excellent...

1 office space

Add to list
2985 National Ave, San Diego, CA 92113

2985 National Ave is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by CBC Corporate.

Honey stop the car!!! Look at this adorable bakery!! Search no longer! This is a full service bakery specializing in Cakes and Everyday Must...

1 office space

Add to list
21 20th St, San Diego, CA 92102

21 20th St is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by CBC Corporate.

Great Opportunity. 3,308 sqft. lot, Industrial Zoned (CN 1-4) Location! Location! Endless Possibilities. Easy Access to 5 freeway. Minutes from...

1 office space

Add to list
1647 Palm Ave, San Diego, CA 92154

1647 Palm Ave is an office property for lease in San Diego, CA. The property currently has 2 office spaces for lease and is marketed by CBC Corporate.

GREAT LOCATION....VERY HIGH TRAFFIC AREA....CLOSE TO IMPERIAL BEACH....

2 office spaces

Add to list
3928 Adams Ave, San Diego, CA 92116

3928 Adams Ave is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by CBC Corporate.

Fantastic opportunity for an investor,owner to own in a very desirable location in the heart of the business district in Normal Heights, Great...

1 office space

Add to list
3734 6th Ave, San Diego, CA 92103

3734 6th Ave is an office property for lease in San Diego, CA. The property currently has 1 office space for lease.

6th Ave in the Balboa Park/Hillcrest area

1 office space

Add to list
1405 Moreno Blvd, San Diego, CA 92110

1405 Moreno Blvd is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by CBC Corporate.

1 office space

Add to list
2751 Imperial Ave, San Diego, CA 92102

2751 Imperial Ave is an office property for lease in San Diego, CA. The property currently has 2 office spaces for lease and is marketed by CBC Corporate.

2 office spaces

Add to list
2953 Imperial Ave, San Diego, CA 92102

2953 Imperial Ave is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by CBC Corporate.

1 office space

Add to list
6575 El Cajon Bl, San Diego, CA 92115

6575 El Cajon Bl is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by CBC Corporate.

1 office space

Add to list
5933-43 El Cajon Boulevard, San Diego, CA 92115

5933-43 El Cajon Boulevard is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by CBC Corporate.

1 office space

Add to list
2795 B St, San Diego, CA 92102

2795 B St is an office property for lease in San Diego, CA. The property currently has 4 office spaces for lease and is marketed by CBC Corporate.

4 office spaces

Add to list
1 2 3 4 5 6 7 8 9 10

Useful Links for San Diego:


Nearby Commercial Real Estate Listings:

Request Property Information

Please describe your commercial real estate requirements in San Diego, CA. We'll create a list of matching properties that meet your criteria.

- Brandon Heath, San Diego agent and Rofo Pro